Eosinophilic Esophagitis Presenting as Complete Esophageal Desquamation: An Unusual Case of Chest Pain

Kheng-Jim Lim, MD, Lanjing Zhang, MD, MS, Anish Sheth, MD

Abstract


The diagnosis of eosinophilic esophagitis has been steadily increasing with the increase usage of endoscopy as a diagnostic tool.  Here we present a case of complete esophageal desquamation visualized on endoscopy without any evidence of caustic ingestion or any other potential disease process that would cause a similar presentation.  The diagnosis of eosinophilic esophagitis was established by significantly increased intraepithelial eosinophils, eosinphilic micro-abscess and partially detached squamous epithelium on the esophageal biopsy. There was complete resolution of symptoms with standard therapy for eosinophilic esophagitis. To the best our knowledge, this is the first reported case in the English literature of eosinophilic esophagitis that presents as complete esophageal desquamation.

Keywords


eosinophilic esophagitis, desquamative esophagitis

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References


Liacouras CA, Furtua GT, Hirano I, et al. Eosinophilic esophagitis: updated consensus recommendations for children and adults. J Allergy Clin Immunol. 2011;128(1):3-20.

Shahzad G, Mustacchia P, Frieri M. Role of mucosal inflammation in eosinophilic esophagitis: Review of the literature. ISRN Gastroenterology. 2011;2011:468073.

Matunaga Y, Goto A, Fujii K, et al. Desquamative esophagitis due to pemphigus vulgaris. Endoscopy. 2010;2(7):252-256.

Fukuchi M, Otake S, Naitoh H, et al. A case of exfoliative esophagitis with pemphigus vulgaris. Dis Esophagus. 2011;24(3):23-25.

Chandan VS, Murray JA, Abraham SC. Esophageal lichen planus. Arch Pathol Lab Med. 2008;132(6):1026-1029.

Westbrook R, Riley S. Esophageal Lichen Planus: Case Report and Literature Review. Dysphagia. 2008;23(3):331-334.

Khamays I, Eliakim R. Esophageal pemphigus vulgaris: a rare manifestation revisited. Gastroenterol Hepatol (NY). 2008;4(1):71-72.

Kanbay M, Selcuk H, Gur G, et al. Involvement of the esophagus in a patient with pemphigus vulgaris who was on immunosuppressive therapy. J Natl Med Assoc. 2006;98(8):1369-1370.

Hokama A, Yamamoto Y, Taira K, et al. Esophagitis dissecans superficialis and autoimmune bullous dermatoses: A review. World J Gastrointest Endosc. 2010;2(7):252-256.


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