An Aggressive Psammomatoid Ossifying Fibroma Presenting as a Sphenoethmoidal Mass

Ngozi N. Nwizu, BDS, MMSc, Mary D. George, MD, Frank Chen, MD, PhD


Aggressive psammomatoid ossifying fibromas are rare, benign fibro-osseous tumors characterized by the presence of numerous calcified spherules within an actively proliferating connective tissue stroma.  They are mainly seen in the sino-naso-orbital region of young individuals.  CT scans tend to show a relatively well delineated heterogeneous mass with varying degrees of radiodensity depending on the amount of calcification present.  As the name implies, they are prone to aggressive behavior and a high rate of recurrence.  We report a case of an aggressive psammomatoid ossifying fibroma presenting as a sphenoethmoidal mass. The relevant histopathological differential diagnoses are also discussed.

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