Parinaud Oculoglandular Syndrome as a Prominent Presenting Feature of Kikuchi-Fujimoto Disease – A Case Report and Review of the Literature

Daniela Hoehn, MD, PhD, Kamalesh K. Bala, MD, PhD, Wen Fan, MD, PhD, C. Cameron Yin, MD, PhD


Kikuchi-Fujimoto disease (KFD) is an often under-diagnosed form of lymphadenitis that clinically mimics lymphoma. Ocular manifestations are rare in patients with KFD and are under-appreciated in the literature. We describe a man who presented with eye redness, blurred vision, and pain on upward gaze associated with fever, weight loss and cervical lymphadenopathy. This presentation was initially interpreted as Parinaud oculoglandular syndrome which is most often caused by infection leading to an infectious workup. Lymph node biopsy was eventually performed and showed KFD. Kikuchi-Fujimoto disease needs to be added to the list of known causes of Parinaud oculoglandular syndrome. 


Parinaud oculoglandular syndrome, Kikuchi-Fujimoto disease, lymphadenopathy

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