Ectopic Hamartomatous Thymoma: A Case Report and Literature Review

Zhiwei Yin, MD, PhD, Ruifang Zheng, MD, PhD, Charvi Cassano, MD, PhD, Ozlem Fidan-Ozbilgin, MD, Shahida Ahmed, MD, Donghong Cai, MD, PhD


Ectopic hamartomatous thymoma is a rare benign tumor located at  supraclavicular/suprasternal area and is speculated with a branchial anlage origin. There are usually 3 components in the tumor: spindle cells, epithelial cells, and adipose tissue, although proportion of each varies from case to case. The tumor cells present with a unique immunophenotype, with strong positivity for AE1/AE3, CD34, CD10, and variable staining for Bcl-2 and SMA. Here we report such a case in a 61 year old male, with a compatible morphology and immunopattern for this entity.

[N A J Med Sci. 2018;11(1):11-14.   DOI:  10.7156/najms.2018.110111]

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