Colonic Mucosal Schwann Cell Hamartoma: A Case Report and Literature Review

Ruifang Zhang, MD, Donghong Cao, MD, PhD


Colonic mucosal Schwann cell hamartoma is an extremely rare entity, presenting as small colonic polyp, associating with no clinical symptoms and harboring no clinical significance. However, its mimics, such as GI neurofibroma/neurofibromatosis,  ganglioneuroma, etc. are possible GI manifestations of hereditary syndromes and therefore are integral part of the patient workup and disease diagnosis. Here we report a case of mucosal Schwann cell hamartoma, with description of its morphology and immunophenotype. We also reviewed literature and differentially described some important mimics.

[N A J Med Sci. 2018;11(1):19-21.   DOI:  10.7156/najms.2018.110119]

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