Trans Fat and Cardiovascular Disease

Qi Sun, MD, ScD


Cardiovascular disease remains the number one killer in the United States. According to the American Heart Association statistics, CVD accounted for 35.2% of total deaths in 2005 in the United States.1 This is also true for developing countries, such as China and India: CVD has also become the first or second leading causes of death; it is responsible for around 30% of total deaths in developing countries.2 Of many risk factors for CVD, dietary intake of fats received much attention and has been extensively studied due to the facts that blood cholesterol levels are a strong predictor for CVD3 and that dietary fats are a strong determinant for serum lipids.4 Although the effects of some fatty acids on coronary health are still a matter of debate, the relationship between trans fatty acids and risk of CVD has been established.5

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