Effects of Simulated Gastrointestinal Digestion on Antioxidant Activities of Individual and Mixed Fruits

Gui-Fang Deng, PhD, Lei Nie, MD, Wen Ai, PhD, Yuan-Huan Wei, MD, Rui-Fang Sun, MD, Xiu-Juan Deng, MD, Hua-Bin Li, PhD


Fruits are important part of dietary pattern and correlated with a lower risk of chronic diseases because they contain many natural antioxidants. The gastrointestinal digestion could affect on antioxidant activities of fruits. In this study, we investigated the effects of simulated gastrointestinal digestion on the antioxidant activities of individual and mixed fruits. In the gastric digestion, the FRAP values of all 11 fruits exhibited a decreased tendency, and the TEAC values showed an increased tendency. The TPC exhibited different results in the 11 fresh fruit samples.  In fruits combination groups, no notable difference was found on the interaction with the FRAP values, and different interactions were detected with the TEAC values (p < 0.05). The gastric process did not make any difference on the TPC between the fruit combinations, but after the duodenal digestion the TPC of group 4 were notably decreased, and the TPC of groups 5 and 8 were increased (p < 0.05). Therefore, the different fruit extracts have different behaviors in tests of FRAP, TEAC, and TPC after the simulated digestion process. Further researches should be done to help explore the mechanisms of the different interactions.

[N A J Med Sci. 2019;12(1):014-020.   DOI:  10.7156/najms.2019.1201014]

Full Text:



  • There are currently no refbacks.