Solar Lentigo Evolving into Fatal Metastatic Melanoma in a Patient Who Initially Refused Surgery

Authors

  • Michael Shatkin, MS New York Medical College, School of Medicine, Valhalla, NY
  • Matthew F Helm, MD* Penn State Hershey Medical Center, Departments of Dermatology and Pathology, Hershey, PA
  • Aaron Muhlbauer, MD Loyola University Medical Center, Department of Pathology, Chicago, IL
  • Catherine G Chung, MD Ohio State University Wexner Medical Center Divisions of Dermatology and Dermatopathology, Columbus, OH

Abstract

Lentigo maligna may not progress to invasive disease for many decades.  We present the unusual case of a woman who underwent well documented periodic evaluations and occasional biopsies of a nasal lesion that gradually progressed from lentigo, to melanoma in situ of lentigo maligna type, to invasive disease, and finally to fatal metastatic melanoma.  She had declined curative resection of her tumor for cosmetic reasons.  Her clinical course is unusual in that photographs and biopsies document the progression from solar lentigo to fatal disease.

[N A J Med Sci. 2020;1(1):028-031.   DOI:  10.7156/najms.2020.1301028]

 

Key Words: melanoma; lentigo maligna; metastasis; squamous cell carcinoma; solar lentigo; unstable lentigo


*Corresponding Author: Penn State Milton S. Hershey Medical Center, Department of Dermatology HU14, 500 University Drive, Suite 100, Hershey, PA 17033. Tel: 717-531-6820, Fax: 717-531-4702. (Email: mhelm2@pennstatehealth.psu.edu)


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Published

2020-08-04

How to Cite

Shatkin, MS, M., Helm, MD*, M. F., Muhlbauer, MD, A., & Chung, MD, C. G. (2020). Solar Lentigo Evolving into Fatal Metastatic Melanoma in a Patient Who Initially Refused Surgery. North American Journal of Medicine and Science, 14(1). Retrieved from https://najms.com/index.php/najms/article/view/538

Issue

Vol. 14 No. 1 (2021)

Section

Case Report