Diagnosis of Concomitant Plasma Cell Myeloma and Chronic Lymphocytic Leukemia in a Single Patient: A Case Report
Abstract
Plasma cell myeloma (PCM) and chronic lymphocytic leukemia (CLL) are hematologic malignancies that occur at different stages of the B-cell maturation pathway. Although both diseases are relatively common malignancies in elderly individuals, their concomitant occurrence in one patient is rare. Here we report a patient with a 9-year history of CLL who was subsequently diagnosed with coexisting PCM after she was found to have bilateral pathologic clavicular fractures. We provide immunohistological and immunophenotypic evidence for these separate and simultaneous diseases within the same patient.
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