Optic Nervev Neuropathy and repair in Gloucoma

Kin-Sang Cho, Dong Feng Chen


Glaucoma is one of the leading causes of impaired vision and blindness worldwide. It is a disease involving progressive optic nerve pathology and retinal ganglion cell (RGC) function loss.1 Optic neuropathy and RGC death are the hallmarks of glaucoma, which are often associated with structural changes in the optic nerve head.2,3 Effective therapeutic strategies to treat neuronal damage and restore vision in glaucoma rely heavily on the knowledge and understanding of the cellular and molecular responses in RGCs and the optic nerve.

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